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First, chronic inflammationprimarily mediated by neutrophils and macrophagesdirectly damages the epithelium and extracellular matrix (ECM) through proteases (e.g., MMPs, elastase), chemokines, and reactive oxygen species, thereby promoting structural destruction and airway narrowing

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Its really not about education other than the more we actually get to know each other, the less we can hate each other almost all the time, except for people that stay in the left lane and go too slow (laughs)